Greek Genome Center: BRFAA

Greek Genome Center

The Greek Genome Center (GGC), established by the Biomedical Research Foundation of the Academy of Athens (BRFAA), focuses on advancing genomic research by providing genomic analyses based on Next Generation Sequencing and High Performance Computing. GGC is equipped with low (Miseq), mid (NextSeq) and high throughput (NovaSeq) Illumina sequencers, supported by automated high throughput DNA extraction and liquid handling workstations. In the few years since its establishment, the GGC has successfully completed numerous sequencing projects for researchers in Greece and abroad and is continuously expanding in terms of productivity and diversity of offered services.

DNA Seq

RNA Seq

DNA/RNA Extraction

Samples Quality Control

Services

DNA-seq

DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. Among others, DNA sequencing is used for identifying:

The complete DNA sequence of an organism’s genome (Whole Genome Seq, WGS)
The precise DNA sequencing of all the protein-coding genes in a genome (Whole Exome Seq, WES) or of a specific group of genes (Gene Panel Seq)
The binding sites of a DNA-associated protein (ChIP-seq)
The DNA regions in the genome associated with regulatory activity (DNAse-seq, FAIRE-seq)
The sequences that act as transcriptional enhancers (STARR-seq)

RNA-seq

A high resolution tool for studying changes in the coding and noncoding regions of the transcriptome. RNA-Seq enables the sensitive and accurate measurement of differential gene expression over time or in different groups, conditions and treatments. RNA-Seq also enables the detection of transcript isoforms, gene fusions, single nucleotide variants (SNVs) and allele-specific gene expression.